Embryo Genetic Testing [A Guide]

Embryo genetic testing is the process of screening embryos created through in-vitro fertilization (IVF) for chromosomal abnormalities before the embryo transfer takes place.

Genetic testing of the embryos can help identify embryos with the best chances of implantation for the embryo transfer.  

Reach out to us today to get more free information about finding a reputable fertility clinic near you that can handle embryo genetic testing for your journey to parenthood.

This article will take a look at preimplantation genetic testing (PGT) in detail, from its role in IVF and what it tests for to how long it takes and its cost.

What Does Genetic Testing of Embryos Show?

Embryo genetic testing, or PGT, assesses your embryos for genetic conditions or chromosomal abnormalities before selecting embryos for transfer.

There are two different types of genetic testing, PGT-A and PGT-M:

PGT-A

PGT-A (preimplantation genetic testing for aneuploidy) evaluates the embryos for chromosomal abnormalities, such as Down syndrome, which can lead to:

PGT-A helps your fertility specialist determine what embryos to transfer.

PGT-M

PGT-M (preimplantation genetic testing for a monogenic disorder) helps prevent you or your partner from passing on known genetic conditions from you or your family, like cystic fibrosis or sickle cell disease, by identifying embryos with these disorders prior to the embryo transfer.

How Are Embryos Screened for Genetic Disorders?

Genetic screening of embryos doesn’t occur at the blastocyst stage.

Once the embryo reaches that stage, the embryo itself is frozen while a number of cells from each embryo are biopsied and sent for additional tests.

Genetic Testing of Embryos: Pros and Cons

PGT ensures that the genetic testing on embryos helps lead to a safer pregnancy. The pros of PGT include:

Although PGT and IVF are well-proven tactics, make sure you talk to your medical team about any concerns with the pros and cons of PGT and its ability to help grow your family.

Pros

Cons

• False Results: There is the potential for false positives or negatives with any type of testing. This could result in viable embryos going unused or being disposed.
• Embryo Damage: Genetic testing of embryos requires the removal of cells for biopsy. Although the risk is low, embryo damage can occur during the removal.
• Additional Cost: Additional genetic testing comes with a cost. IVF is an expensive process already and insurance may or may not cover genetic testing either.

Does Genetic Testing Damage Embryos?

How an embryo is handled, from the removal of cells for PGT to the freezing and thawing of the embryo, can lead to enough damage to an embryo where it will not lead to implantation.

Although there is the potential for damage with the genetic testing on an embryo, that potential is minimal with only about 5% of embryos that have PGT done being lost due to damage.

Is Embryo Genetic Testing Worth It?

Embryo genetic testing can be highly beneficial in certain IVF scenarios, but whether it’s “worth it” depends on individual circumstances, health history and family goals.

PGT could be right for your situation if you:

Contact us online to get connected to reputable fertility clinics near you that can walk you through their process for the genetic screening of embryos.